Women who have hypertensive diseases during pregnancy seem to be at higher risk of having troublesome hot flashes and night sweats at menopause, report researchers from the Netherlands in an article published online today in Menopause, the journal of The North American Menopause Society. This is the first study to look at this association. Eurekalert!
Glucocorticoids Boost Risk of Blood Clots (CME/CE)
Glucocorticoid use significantly increased the risk of venous thromboembolism (VTE) among current, new, and continuing users of the anti-inflammatory agents, data from a large case-control population showed. Steroid users had two to three times the VTE rate of nonusers and former users. Cumulative doses ≥1,000 mg increased VTE risk by 60% to 98% as compared with a prednisone-equivalent cumulative dose ≤10 mg. MedPage Today
New Med School Aims to Train Primary Care Docs
Michael Ellison has a tough assignment. He's the associate dean of admissions choosing the first class of a brand new medical school, the Frank H. Netter MD School of Medicine at Quinnipiac University in Connecticut. It's a school with a very specific mission: minting new doctors who want to go into primary care practice. MedPage Today
The effect of Helicobacter pylori on gastroesophageal reflux disease
Controversy still exists about the association between GERD and HP infection. Based on our findings, significant evidence suggests the potential role of HP infection in the development of GERD. Also, the current data provide sufficient evidence to define the relationship between GERD and HP infection. Polat FR, Polat S. JSLS. 2012 Apr-Jun;16(2):260-3. PMID: 23477175
Empirical evidence of the importance of comparative studies of diagnostic test accuracy
Evidence derived from noncomparative studies often differs from that derived from comparative studies. Robustly designed studies in which all patients receive all tests or are randomly assigned to receive one or other of the tests should be more routinely undertaken and are preferred for evidence to guide test selection.
Takwoingi Y, Leeflang MM, Deeks JJ. Ann Intern Med. 2013 Apr 2;158(7):544-54. PMID: 23546566
Medical management to prevent recurrent nephrolithiasis in adults: a systematic review for an american college of physicians clinical guideline
In patients with 1 past calcium stone, increased fluid intake reduced recurrence risk. In patients with multiple past calcium stones, addition of thiazide, citrate, or allopurinol further reduced risk. Fink HA, Wilt TJ, Eidman KE, Garimella PS, Macdonald R, Rutks IR, Brasure M, Kane RL, Ouellette J, Monga M.
Ann Intern Med. 2013 Apr 2;158(7):535-43. PMID: 23546565
Integrative review: evidences on the practice of intermittent/indwelling urinary catheterization
There are controversies in relation to periurethral cleansing technique, the type of material the catheter is made of, and some procedures for the maintenance and removal of the catheter. This review's results represent an updating of the nurse's conducts and decision-making for the prevention of urinary tract infections in urinary catheterization. Ercole FF, Macieira TG, Wenceslau LC, Martins AR, Campos CC, Chianca TC. Rev Lat Am Enfermagem. 2013 Feb;21(1):459-68. English, Portuguese, Spanish. PMID: 23546332
Breakthrough cancer-killing treatment has no side-effects
Cancer painfully ends more than 500,000 lives in the United States each year, according to the Centers for Disease Control and Prevention. The scientific crusade against cancer recently achieved a victory under the leadership of University of Missouri Curators' Professor M. Frederick Hawthorne. Hawthorne's team has developed a new form of radiation therapy that successfully put cancer into remission in mice. This innovative treatment produced none of the harmful side-effects of conventional chemo and radiation cancer therapies. Clinical trials in humans could begin soon after Hawthorne secures funding. Eurekalert!
New relief for gynecological disorders
The creation of new blood vessels in the body, called "angiogenesis," is usually discussed in connection with healing wounds and tumors. But it's also an ongoing process in the female reproductive tract, where the growth and breaking of blood vessels is a normal part of the menstrual cycle. But abnormal growth of blood vessels can have painful consequences and resultant pathologies. MedicalXpress
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