CAM

Oregon researchers say supplement cuts muscle loss in knee replacements
In the study, 12 members of a control group receiving 40 grams a day of a non-essential amino acid supplement, a placebo, averaged an 18.4 loss in quadriceps muscle mass in their operated leg six weeks after surgery; those getting the supplement of eight essential amino acids (EEA) averaged a 6.2 percent loss. Eighty percent of atrophy occurred in the first two weeks after surgery. Atrophy in non-operative legs was about 50 percent of that in the operative leg in both groups. Muscle mass changes were seen with magnetic resonance imaging done at two and six weeks after surgery. Eurekalert!

Excess omega-3 fatty acids could lead to negative health effects
Omega-3 fatty acids have anti-inflammatory properties, which is one of the reasons they can be beneficial to heart health and inflammatory issues. However, the researchers said excess amounts of omega-3 fatty acids can alter immune function sometimes in ways that may lead to a dysfunctional immune response to a viral or bacterial infection. Eurekalert!

Chalcone and Curcumin Derivatives: A Way ahead for Malarial Treatment Curcumin and chalcones has been reported to exert anti-malarial effect by binding directly to numerous signaling molecules, such as histone acetyltransferase, histone deacetylase, sarco (endo) plasmic reticulum Ca2+ ATPase, cysteine proteases etc. This review highlights insights into more recent antimalarial activities of these compounds, their mechanisms of action, molecular targets and relevant structure-activity relationships studies. Kumar D, Kumar M, Kumar A, Singh SK. Mini Rev Med Chem. 2013 Oct 25. [Epub ahead of print] PMID: 241607