A novel single molecule hormone, which acts equally on the receptors of the insulin-stimulating hormones GLP-1 and GIP, was observed to reduce weight and improve blood sugar. The results have now been published in the medical journal 'Science Translational Medicine', and include data from successful clinical studies in partnership with the pharmaceutical company Roche. Helmholtz Zentrum München
HDL cholesterol controls blood glucose
High density lipoprotein cholesterol (HDL), the so-called “good“ cholesterol improves blood glucose levels by enhancing skeletal muscle function and reducing adiposity, scientists of the Helmholtz Zentrum München report in the current issue of the renown American Heart Association Journal ‚Circulation‘. Helmholtz Zentrum München
A therapeutic hypothesis for glucose intolerance after cerebral ischemia
The researchers believed that glucose intolerance after cerebral ischemia can be improved by suppressing the loss of brain-derived neurotrophic factor in the hypothalamus. These findings were published in the Neural Regeneration Research. Eurekalert!
Bacteria and fat: A 'perfect storm' for inflammation, may promote diabetes
The UI researchers used immortalized fat cells to show that bacterial toxins stimulate fat cells to release molecules called cytokines, which promote inflammation. By immortalizing fat cells the UI team created a stockpile of continuously dividing, identical cells that are necessary for repeat experiments to validate results, explains Al Klingelhutz, Ph.D., UI microbiologist and co-senior author of the study. MedicalXpress
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