Glucose Targets in Pregnant Women With Diabetes: A Systematic Review and Meta-Analysis
Evidence warranting very low confidence in the estimates suggests that a fasting glucose target of < 90 mg/dL is associated with a lower risk of macrosomia and other outcomes of different importance in women with gestational diabetes. Whether this target can be extrapolated to women with pregestational diabetes or whether targets above or below this threshold offer a better benefit/risk balance remains unclear. Prutsky GJ, Domecq JP, Wang Z, Carranza Leon BG, Elraiyah T, Nabhan M, Sundaresh V, Vella A, Montori VM, Murad MH. J Clin Endocrinol Metab. 2013 Oct 22. [Epub ahead of print] PMID: 24151289
Screening for Gestational Diabetes: A Systematic Review and Meta-analysis
Indirect evidence supports the use of contemporary screening tests for GDM to identify pregnancies at increased risk of adverse feto-maternal outcomes. It also suggests that use of these tests will place some women under unnecessary treatment for GDM. Prutsky GJ, Domecq JP, Sundaresh V, Elraiyah T, Nabhan M, Prokop LJ, Vella A, Montori VM, Murad MH. J Clin Endocrinol Metab. 2013 Oct 22. [Epub ahead of print] PMID: 24151288
Single dose oral dexibuprofen [S(+)-ibuprofen] for acute postoperative pain in adults
The information from these two studies in acute postoperative pain suggested that dexibuprofen may be a useful analgesic, but at doses not very different from racemic ibuprofen, for which considerably more evidence exists. Derry S, Best J, Moore RA. Cochrane Database Syst Rev. 2013 Oct 23;10:CD007550. [Epub ahead of print] PMID: 24151035
An intragastric balloon in the treatment of obese individuals with metabolic syndrome: a randomized controlled study
Statistically significant and clinically relevant improvements in weight loss and health outcomes were observed with the IGBG at 6 months versus behavioral modification alone. The differential weight loss was still evident 6 months after IGB removal. Evidence Updates
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