Scientists discover why newborns get sick so often
If you think cold and flu season is tough, trying being an infant. A new research finding published in the November 2013 issue of the Journal of Leukocyte Biology sheds new light on why newborns appear to be so prone to getting sick with viruses—they are born without one of the key proteins needed to protect them. This protein, called "toll-like receptor 3" or "TLR3," is involved in the recognition of different viruses and mediates the immune response to them. Without this protein, newborn immune cells are not equipped to recognize and react appropriately to certain viruses, in particular, the herpes simplex virus known as HSV. Eurekalert!
US preterm birth rate drops to 15-year low
Six states – Alaska, California, Maine, New Hampshire, Oregon and Vermont – earned an "A" on the March of Dimes 2013 Premature Birth Report Card as their preterm birth rates met the March of Dimes 9.6 percent goal. The US preterm birth rate improved to the lowest rate in 15 years, but the change wasn't enough to earn it a better grade. The nation again earned a "C" on the Report Card. Eurekalert!
Combined and alternating paracetamol and ibuprofen therapy for febrile children
There is some evidence that both alternating and combined antipyretic therapy may be more effective at reducing temperatures than monotherapy alone. However, the evidence for improvements in measures of child discomfort remains inconclusive. There is insufficient evidence to know which of combined or alternating therapy might be more beneficial.Future research needs to measure child discomfort using standardized tools, and assess the safety of combined and alternating antipyretic therapy. Wong T, Stang AS, Ganshorn H, Hartling L, Maconochie IK, Thomsen AM, Johnson DW. Cochrane Database Syst Rev. 2013 Oct 30;10:CD009572. [Epub ahead of print] PMID: 24174375
The role of L-arginine in the prevention and treatment of pre-eclampsia: a systematic review of randomised trials
L-arginine may have a role in the prevention and/or treatment of pre-eclampsia. Further well-designed and adequately powered trials are warranted, both in women at risk of pre-eclampsia and in women with established disease. Dorniak-Wall T, Grivell RM, Dekker GA, Hague W, Dodd JM. J Hum Hypertens. 2013 Oct 31. [Epub ahead of print] PMID: 24172291
Recurrent epistaxis in children
In this systematic review we present information relating to the effectiveness and safety of the following interventions: antiseptic cream (containing chlorhexidine hydrochloride, neomycin sulfate, or both), petroleum jelly, and silver nitrate cautery. McGarry GW. Clin Evid (Online). 2013 Oct 30;2013. PMID: 24172703
Is it a boy or a girl? Germany allows babies to be neither
Germany on Friday became the first European country to allow babies born with characteristics of both sexes to be registered as neither male nor female, but advocates urged further reforms. Under the new legislation, the field for gender can be left blank on birth certificates, effectively creating a category for indeterminate sex in the public register. MedicalXpress
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