Friday, February 7, 2014

CAM

Walnuts Have Potential for Cancer Prevention and Treatment in Mice
 Mouse studies in which walnuts were added to the diet have shown the following compared with the control diet: 1) the walnut-containing diet inhibited the growth rate of human breast cancers implanted in nude mice by ∼80%; 2) the walnut-containing diet reduced the number of mammary gland tumors by ∼60% in a transgenic mouse model; 3) the reduction in mammary gland tumors was greater with whole walnuts than with a diet containing the same amount of n-3 fatty acids, supporting the idea that multiple components in walnuts additively or synergistically contribute to cancer suppression; and 4) walnuts slowed the growth of prostate, colon, and renal cancers by antiproliferative and antiangiogenic mechanisms. Cell studies have aided in the identification of the active components in walnuts and of their mechanisms of action. Hardman WE. J Nutr. 2014 Feb 5. [Epub ahead of print] PMID: 24500939

Resveratrol and cancer: a focus on in vivo evidence
Much of the work on resveratrol and cancer comes from in vitro studies looking at resveratrol actions on cancer cells and pathways. There are, however, comparatively fewer studies that have investigated resveratrol treatment and cancer outcomes in vivo, perhaps limited by its poor bioavailability when taken orally. Although research in cell culture has shown promising and positive effects of resveratrol, evidence from rodents and humans is inconsistent. This review highlights the in vivo effects of resveratrol treatment on breast, colorectal, liver, pancreatic, and prostate cancers. Carter LG, D'Orazio JA, Pearson KJ. Endocr Relat Cancer. 2014 Feb 5. [Epub ahead of print] PMID: 24500760

A systematic review of yoga for heart disease
Based on the results of this review, weak recommendations can be made for the ancillary use of yoga for patients with coronary heart disease, heart failure, and cardiac dysrhythmia at this point. Cramer H, Lauche R, Haller H, Dobos G, Michalsen A. Eur J Prev Cardiol. 2014 Feb 3. [Epub ahead of print] PMID: 24491402

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